Legitimate employers will not ask you for money. When applying for any job, whether at home or in a brick and mortar facility, remember you are working for them, therefore they pay you. Some typical requests from employers who have at home job listings include: high speed internet access, personal computer or laptop available during all working hours, unlimited phone access, and a local printer. If any employer ever asks for money directly, please contact the Better Business Bureau. As with all jobs listed on the Internet, make sure you research them thoroughly before giving personal information.
Other "career" opportunities include legitimate companies which offer at home positions, but they are not legally defined as "jobs." These companies, such as Avon, Tupperware and Mary K, offer a career opportunity for a fee. Be careful upon choosing a career such as this and make sure you understand all the fees up front as well as continuous fees the company may charge for use of their property. Also, be aware that some of these companies ask for a large sum of money to stock personal inventory, but there are few of these out there these days.
This site has many avenues listed of making money at home, whether it be a career, home business, or job. To find an at home job, browse the below table, try the job search to the right (copy and paste the bold print into a search engine), or navigate to the known employers list at Telecommute Job Finder.